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Psychol Med 28:285293 Shungu DC, Weiduschat N, Murrough JW et al (2012) Increased ventricular lactate in chronic fatigue syndrome

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In AD animal models, M1-polarized microglia frequently co-exist with iron accumulation, indicating a synergistic interaction between inflammatory activation and disrupted iron metabolism in driving neurotoxicity (Mendoza and Scharff, 2017)

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They exhibit the potential to enhance the pharmacokinetics of drugs, such as tacrolimus, for the treatment of ocular diseases like dry eye [74]

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MC1R in peripheral melanocytes driving melanogenesis, and central MC3R/MC4R in hypothalamic and limbic circuits driving sexual behaviour

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